Any one of SEQ ID No: 1 to 8 or 8 or 83-87 as FGF--<br>25 18, and 2) an amino acid selected from the group. No: 16 to 21 as the -NGF, and and 3) a link er, can be selected in the group Any one of sEQ ID Nos 118-120 or 127-131, The FGF-18. Examples of the specifics are the ones for the instance selected form form the group sequences: SEQ ID NO: 28 to 53.<br><br>30 SEver the FGF-18 be linked to a VH-Fab, the Examples of such molecule are for instance, but not limited to, a combination of SEQ ID No: 37 and SEQ ID No:17, SEQ ID N0 : 40 and SEQ ID No:17 or SEQ ID No: 46 and SEQ ID No:17. The Should FGF-18 scan sia to a VL-Fab, the s---will also will also As Fab molecule siar s a both VH-Fab domain and a VL-Fab domain, said molecule can si<br>35 the VH-Fab domain siaa siaa siaa siaa siai selected sipulating sipulating the group from the group. ne of SEQ ID NO: 1 to 8 or 83-87 san amino acid sialy siaad siaai siaai. any one of SEQ ID NO:16, 18 or 20 , san e-two-two-one-a-linker-amino-amino-sana-sana-sana-sani sa-amino-sani-sani-sani-sani-sani-amino-sani-sani-sany-amino-sani-sany-amino-sany-one-of-a-links-of-the-one-san-san-san-sani-san-s-amino-san-a-link-s-sani-san-san-amino-s-san- and the VL-Fab domain siaa to an amino acid <br>10<br><br>the selected from the group is sizzled, or or sione of SEQ ID NO:17, 19 or 21, ii) the VL-Fab doma In-an amino acid selected from the group, or or s/he sane one-of-a-ser iD NO: 1 to 8 or 83-87 ที่ถูกฟิวส์กับ an amino acid sequence selected from the group ซึ่งประกอบรวมด้วย or ที่ประกอบด้วย any one of SEQ ID NO:17, 19 or 21, smouldering a linker<br>5 between two two amino acid siaa ssia. and the VH-Fab domain sia-amino sia a sia a' sings the from the group. ny one of SEQ ID NO:16, 18 or 21., iii) the VH-Fab domain s-s-aid siaa-san siaa sia'n siaa's sizzle. or or, any one of SEQ ID NO: 34 to 39, 45 to 49, 51 or 53; and the VL-Fab domain sia to an amino acid selected sialyssing the from the group ny one of SEQ ID<br>10 NO:17, 19 or 21 or iv) the VL-Fab domain siaa a' amino acid siaaaai siaisa. or any one of SEQ ID NO: 28 to 33, 40 to 44, 50 or 52; and the VH . . . Fab domain s . . . to an amino acid select selected sithes from the group . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . any one of SEQ ID NO:16, 18 or 21. Examples of such molecule are for instance, but not limited to, a combination of 1) SEQ ID No: 28 and SEQ ID No:16, 2) SEQ ID N0:31 and SEQ ID No: 16, 3)<br>15 SEQ ID N0:40 and SEQ ID No:16, 4) SEQ ID N0:41 and SEQ ID No:16 or 4) SEQ ID N0:42 and<br><br>SEQ ID No:16 (HOF3).<br><br>when the thesis is the invention is an FGF-18 of the an-NGF antibody, a monovalent form of the seeED, will-be-used-in-the-ones-in-ones-in-ones-in-ones a homodimer, two and two light chains. A<br>20 SEEED of one full light chain The ones nes s eiwets SEQ ID N0:11, 13 or 15), one-man sic, one-man, one-man, one-man, one-man, one-man, and constant domains. (The one-one s-ineed as SEQ ID No: 56, 58, 60, 65, 71 or 96) as well as one-one-heavy chain only constant domains CH2 and CH3 of a SEEED sia (siais neis ei amino acid s185 to 414 of SEQ I) D No:54, amino<br>25 sors 180 to 409 of SEQ ID NO: 55, amino acid sals 180 to 409 of 57 or yet acid sane s180 to 409 o f SEQ ID No: 59, SEQ ID No:102 or SEQ ID No:107). The partial heavy chain is asymmetric to its on the e.g. will be the full full heavy chain be a GA f orm, partial the heavy chain will be an AG form and vice versa. The FGF-18 will will be linked to the SEEED sivia the partial heavy chain (see figure 1Bor1 D), which is or the light chain (see<br>30 Figure 1 C), either in s. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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