overcooling the body can be fatal. The systems for cooling and heating show an interesting asymmetry: Cold-sensitive neurons in the spinal cord respond to a drop in temperature. For example, a cell that responds to a drop from 39° C to 33° C would also respond to a drop from 33° C to 27° C. Thus, on avery hot day, you might detect a breeze as “cool,” even though the air in the breeze is fairly warm. Cold-sensitive neurons adapt quickly, and show little response to a constant low temperature. In contrast, heat-sensitive neurons in the spinal cord respond to the absolute temperature, and they do not adapt. A cell that responds to 44° C will respond the same way regardless of whether the skin was hotter, cooler, or the same temperature a minute or two ago (Ran, Hoon, & Chen, 2016).
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